Table 1. Clinical features of North American Lyme disease |
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Findings |
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|
Constitutional |
Skin |
Nervous System |
Cardiac |
Rheumatologic |
Stage I |
Fever, malaise, and regional lymphadenopathy with or without arthralgia/arthritis |
Erythema migrans with a more acute onset, less central clearing, rapid enlargement, and multiple foci uncommon |
-- |
-- |
-- |
Stage II |
-- |
Multiple erythema migrans |
Headache, neck stiffness, and meningisimus with or without cranial neuropathy |
Atrioventricular block and myocarditis |
Severe asymmetric, oligoarticular joint inflammation |
Stage III |
-- |
Rare |
Paresthesias, radiculopathy, sleep disturbance, and cognitive deficits such as impaired memory and impaired concentration |
None |
Occasional treatment-resistant arthritis |